Senior Principal Research Scientist, Protein Sciences Job at IDEAYA Biosciences, South San Francisco, CA

  • IDEAYA Biosciences
  • South San Francisco, CA

Job Description

IDEAYA Biosciences seeks an experienced Senior Principal Research Scientist to lead protein production and characterization efforts for oncology drug discovery. The role combines hands-on laboratory work with team supervision, focusing on recombinant protein expression, purification, and support for multiple precision medicine programs.

Responsibilities

  • Conduct hands-on protein expression, purification, and optimization for drug-discovery programs
  • Develop construct designs and troubleshoot challenging proteins and protein complexes
  • Supervise and mentor research associates and PhD-level scientists on the team
  • Coordinate with internal functions and external CROs to deliver fit-for-purpose protein reagents
  • Communicate scientific strategies and findings to project teams and research leadership

Requirements

  • PhD with 9+ years hands-on recombinant protein production expertise
  • Deep knowledge of bacterial and insect-cell expression systems
  • Proven ability to develop and troubleshoot complex protein purification strategies
  • Proficiency with protein characterization methods including SEC, thermal stability, and aggregation assessment
  • Experience selecting, managing, and coordinating external CROs for protein services
  • Ability to supervise and mentor research scientists and associates

Job Tags

Similar Jobs

AbbVie Inc.

Director, Global Security & Business Support, Americas Job at AbbVie Inc.

 ..., Instagram , X and YouTube. Job Description The Director, Security, Americas is responsible for leading the development, implementation...  ...and operational oversight for security support to AbbVie Global Security initiatives and programs in assigned region.... 

AECOM

Wetland Scientist Job at AECOM

 ...applied Wetland Science experience including proficiency in performing Field-Based Three Parameter (Hydrophytes, Hydric Soils and Hydrology) Jurisdictional Wetland Delineation, completing data evaluations, technical report writing and experience with Wetlands Regulations... 

Eurofins USA Material Sciences

Materials Scientist, Dual Beam Analysis Job at Eurofins USA Material Sciences

Eurofins EAG Laboratories has over 40 years experience in engineering and materials testing services. Our parent company, Eurofins Scientific, is a multi-billion-dollar global leader in engineering and scientific services operating over 950 labs in 60 countries with...

Mohawk Industries

Warehouse Associate II Honolulu HI 1st Shift ***20.00 an hour*** Job at Mohawk Industries

 ...a good attendance record. Work within a team environment Expected base pay rate for this role will be between 19.00 and 20.00 per hour at the commencement of employment. However, base pay if hired will be determined on an individualized basis and is only part of... 

Confidential

Beijing A level Biology Teacher Job at Confidential

A level biology teacher wanted for public school in Beijing Job details: position:A level biology teacher*1Student age: 15-18School...  ...permit Requirements: Native English speaker Bachelor degree or above 2 years related a level teaching experience...